von Willebrandís DNA Test
VetGen's DNA test findings can be extremely valuable when
developing and implementing your breeding plans. The chart provided below
outlines the implications of various breeding pair combinations. Remember, it is
always best to breed "Clear to Clear". If followed by all breeders,
these strategies will ensure a significant reduction in the frequency of the
targeted disease gene in future generations of dogs. However, to maintain a
large enough pool of good breeding stock, it may be necessary for some breeders
to breed "Clear" to "Carriers" (see below).
Ideal Breeding Pair. Puppies will
not have the disease gene (neither as Carrier nor as Affected).
Breeding Is Safe. No Affected
puppies will be produced. However, some or all puppies will be Carriers.
Accordingly, it is recommended that Carrier dogs which are desirable for
breeding be bred with Clear dogs in the future, which will produce 50% carrier
and 50% clear animals, to further reduce the disease gene frequency. These
offspring should be tested by VetGen's test for this defective gene, and if
possible, only the clear animals in this generation should be used.
High Risk Breeding. Some puppies
are likely to be Carriers and some puppies are likely to be Affected. Even
though it is possible that there will be some clear puppies when breeding
"Carrier to Carrier", in general, neither this type of breeding pair
nor "Carrier to Affected" are recommended for breeding.
Breeding Not Recommended. -
All puppies will be genetically and medically affected
** In the case of Type l vWD - All puppies will be genetically Affected.
The above information is courtesy of Vetgen - full details can be found by following the link below.